Marijuana is a green or gray mixture of dried, shredded flowers and leaves of the hemp plant Cannabis sativa. There
are over 200 slang terms for marijuana including "pot," "herb," "weed," "boom," "Mary Jane," "gangster," and "chronic."
It is usually smoked as a cigarette (called a joint or a nail) or in a pipe or bong. In recent years, it has appeared in
blunts. These are cigars that have been emptied of tobacco and re-filled with marijuana, often in combination with another
drug, such as crack. Some users also mix marijuana into foods or use it to brew tea.
The main active chemical in marijuana is THC (delta-9-tetrahydrocannabinol). In 1988, it was discovered that the membranes of certain nerve cells contain protein receptors that bind THC. Once securely in place, THC kicks off a series of cellular reactions that ultimately lead to the high that users experience when they smoke marijuana.
The short term effects of marijuana use include problems with memory and learning; distorted perception; difficulty in thinking and problem-solving; loss of coordination; and increased heart rate, anxiety, and panic attacks.
Scientists have found that whether an individual has positive or negative sensations after smoking marijuana can be influenced by heredity. A recent study demonstrated that identical male twins were more likely than non identical male twins to report similar responses to marijuana use, indicating a genetic basis for their sensations. Identical twins share all of their genes, and fraternal twins share about half. Environmental factors such as the availability of marijuana, expectations about how the drug would affect them, the influence of friends and social contacts, and other factors that would be different even for identical twins also were found to have an important effect; however, it also was discovered that the twins' shared or family environment before age 18 had no detectable influence on their response to marijuana.
Cannabis products are usually smoked. Their effects are felt within minutes, reach their peak in 10 to 30 minutes, and may linger for two or three hours. The effects experienced often depend upon the experience and expectations of the individual user as well as the activity of the drug itself.
Low doses tend to induce a sense of well-being and a dreamy state of relaxation, which may be accompanied by a more vivid sense of sight, smell, taste, and hearing as well as by subtle alterations in thought formation and expression. This state if intoxication may not be noticeable to an observer. However, driving, occupational or household accidents may result from a distortion of time and space relationships and impaired coordination.
Stronger doses intensify reactions. The individual may experience shifting sensory imagery, rapidly fluctuating emotions, a flight of fragmentary thoughts with disturbed associations, an altered sense of self-identity, impaired memory, and a dulling of attention despite an illusion of heightened insight. High doses may result in image distortion, a loss of personal identity, and fantasies and hallucinations.
Marijuana contains known toxins and cancer-causing chemicals which are stored in fat cells for as long as several months. Marijuana users experience the same health problems as tobacco smokers, such as bronchitis, emphysema and bronchial asthma. Some of the effects of marijuana use also include: an increased heart rate, dryness of the mouth, reddening if the eyes, impaired motor skills and concentration, and frequent hunger and an increased desire for sweets. Extended use increases risk to the lungs and reproductive system, as well as suppression of the immune system. Occasionally hallucinations, fantasies and paranoia are reported.
Researchers have found that THC changes the way in which sensory information gets into and is acted on by the hippocampus. This is a component of the brain's limbic system that is crucial for learning, memory, and the integration of sensory experiences with emotions and motivations. Investigations have shown that neurons in the information processing system of the hippocampus and the activity of the nerve fibres are suppressed by THC. In addition, researchers have discovered that learned behaviours, which depend on the hippocampus, also deteriorate.
Recent research findings also indicate that long-term use of marijuana produces changes in the brain similar to those seen after long-term use of other major drugs of abuse.
Someone who smokes marijuana regularly may have many of the same respiratory problems that tobacco smokers have. These individuals may have daily cough and phlegm, symptoms of chronic bronchitis, and more frequent chest colds. Continuing to smoke marijuana can lead to abnormal functioning of lung tissue injured or destroyed by marijuana smoke.
Regardless of the THC content, the amount of tar inhaled by marijuana smokers and the level of carbon monoxide absorbed are three to five times greater than among tobacco smokers. This may be due to the marijuana users inhaling more deeply and holding the smoke in the lungs.
Recent findings indicate that smoking marijuana while shooting up cocaine has the potential to cause severe increases in heart rate and blood pressure. In one study, experienced marijuana and cocaine users were given marijuana alone, cocaine alone, and then a combination of both. Each drug alone produced cardiovascular effects; when they were combined, the effects were greater and lasted longer. The heart rate of the subjects in the study increased 29 beats per minute with marijuana alone and 32 beats per minute with cocaine alone. When the drugs were given together, the heart rate increased by 49 beats per minute, and the increased rate persisted for a longer time. The drugs were given with the subjects sitting quietly. In normal circumstances, an individual may smoke marijuana and inject cocaine and then do something physically stressful that may significantly increase risks of overload on the cardiovascular system.
A study of college students has shown that critical skills related to attention, memory, and learning are impaired among people who use marijuana heavily, even after discontinuing its use for at least 24 hours. Researchers compared 65 "heavy users," who had smoked marijuana a median of 29 of the past 30 days, and 64 "light users," who had smoked a median of 1 of the past 30 days. After a closely monitored 19- to 24-hour period of abstinence from marijuana and other illicit drugs and alcohol, the undergraduates were given several standard tests measuring aspects of attention, memory, and learning. Compared to the light users, heavy marijuana users made more errors and had more difficulty sustaining attention, shifting attention to meet the demands of changes in the environment, and in registering, processing, and using information. The findings suggest that the greater impairment among heavy users is likely due to an alteration of brain activity produced by marijuana.
Longitudinal research on marijuana use among young people below college age indicates those who used have lower achievement than the non-users, more acceptance of deviant behaviour, more delinquent behaviour and aggression, greater rebelliousness, poorer relationships with parents, and more associations with delinquent and drug-using friends.
Research also shows more anger and more regressive behaviour (thumb sucking, temper tantrums) in toddlers whose parents use marijuana than among the toddlers of non-using parents.
Any drug of abuse can affect a mother's health during pregnancy, and this is a time when she should take special care of herself. Drugs of abuse may interfere with proper nutrition and rest, which can affect good functioning of the immune system. Some studies have found that babies born to mothers who used marijuana during pregnancy were smaller than those born to mothers who did not use the drug. In general, smaller babies are more likely to develop health problems.
A nursing mother who uses marijuana passes some of the THC to the baby in her breast milk. Research indicates that the use of marijuana by a mother during the first month of breast-feeding can impair the infant's motor development (control of muscle movement).
A drug is addicting if it causes compulsive, often uncontrollable drug craving, seeking, and use, even in the face of negative health and social consequences. Marijuana meets this criterion. More than 120,000 people seek treatment per year for their primary marijuana addiction. In addition, animal studies suggest marijuana causes physical dependence, and some people report withdrawal symptoms.
The NIDA-funded MTF provides an annual assessment of drug use among 12th, 10th, and 8th grade students and young adults nationwide. After decreasing for over a decade, marijuana use among students began to increase in the early 1990s. From 1996 to 1997, use of marijuana at least once (lifetime use) increased among 12th and 10th graders, continuing the trend seen in recent years. The seniors' rate of lifetime marijuana use is higher than any year since 1987, but all rates remain well below those seen in the late 1970s and early 1980s. Past year and past month marijuana use did not change significantly from 1996 to 1997 in any of the three grades, suggesting the sharp increases of recent years may be slowing. Daily marijuana use in the past month increased among 12th graders, but decreased among 8th graders; this pattern of increases among older students and stable or declining rates among younger students was found with several indicators in the 1997 MTF.
| 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | |
|---|---|---|---|---|---|---|---|
| Ever Used | 10.2% | 11.2% | 12.6% | 16.7% | 19.9% | 23.1% | 22.6% |
| Used in the Past | 6.2% | 7.2% | 9.2% | 13.0% | 15.8% | 18.3% | 17.7% |
| Used in the Past Month | 3.2% | 3.7% | 5.1% | 7.8% | 9.1% | 11.3% | 10.2% |
| Daily Use in Past Month | 0.8% | 0.8% | 1.0% | 2.2% | 2.8% | 3.5% | 3.7% |
| 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | |
|---|---|---|---|---|---|---|---|
| Ever Used | 23.4% | 21.4% | 24.4% | 30.4% | 34.1% | 39.8% | 42.3% |
| Used in the Past | 16.5% | 15.2% | 19.2% | 25.2% | 28.7% | 33.6% | 34.8% |
| Used in the Past Month | 8.7% | 8.1% | 10.9% | 15.8% | 17.2% | 20.4% | 20.5% |
| Daily Use in Past Month | 0.8% | 0.8% | 1.0% | 2.2% | 2.8% | 3.5% | 3.7% |
| 1991 | 1992 | 1993 | 1994 | 1995 | 1996 | 1997 | |
|---|---|---|---|---|---|---|---|
| Ever Used | 36.7% | 32.6% | 35.3% | 38.2% | 41.7% | 44.9% | 49.6% |
| Used in the Past | 23.9% | 21.9% | 26.0% | 30.7% | 34.7% | 35.8% | 38.5% |
| Used in the Past Month | 13.8% | 11.9% | 15.5% | 19.0% | 21.2% | 21.9% | 23.7% |
| Daily Use in Past Month | 2.0% | 1.9% | 2.4% | 3.6% | 4.6% | 4.9% | 5.8% |
Community Epidemiology Work Group (CEWG)
The resurgence in marijuana use continues, especially among adolescents, with rates of emergency department mentions of marijuana increasing from 1994 to 1995 in 10 cities, the percentage of treatment admissions increasing in 13 areas, and the National Institute of Justice's Drug Use Forecasting (DUF) percentages increasing among juvenile arrests at numerous sites. In several cities, such as Minneapolis/St. Paul, increasing treatment figures have been particularly notable among juveniles. Two factors may be contributing to the dramatic leap in adverse consequences: higher potency and the use of marijuana mixed with or in combination with other dangerous drugs.
National Household Survey on Drug Abuse (NHSDA)
Marijuana remains the most commonly used illicit drug in the United States. There were an estimated 2.4 million people who started using marijuana in 1995. According to data from the 1996 NHSDA, more than 68.6 million Americans (32 percent) 12 years of age and older have tried marijuana at least once in their lifetimes, and almost 18.4 million (8.6 percent) had used marijuana in the past year. In 1985, 56.5 million Americans (29.4 percent) had tried marijuana at least once in their lifetimes, and 26.1 million (13.6 percent) had used marijuana within the past year.
Some immediate physical effects of marijuana include:
No scientific evidence indicates that marijuana improves hearing, eyesight, and skin sensitivity.
Marijuana use increases the heart rate as much as 50 percent, depending on the amount of THC. It can cause chest pain in people who have a poor blood supply to the heart - and it produces these effects more rapidly than tobacco smoke does. Scientists believe that marijuana can be especially harmful to the lungs because users often inhale the unfiltered smoke deeply and hold it in their lungs as long as possible. Therefore, the smoke is in contact with lung tissues for long periods of time, which irritates the lungs and damages the way they work.
Marijuana smoke contains some of the same ingredients in tobacco smoke that can cause emphysema and cancer. In addition, many marijuana users also smoke cigarettes; the combined effect of smoking these two substances creates an increased health risk. "Burnout" is a term first used by marijuana smokers themselves to describe the effect of prolonged use.
Young people who smoke marijuana heavily over long periods of time can become dull, slow moving, and inattentive. These "burned-out" users are sometimes so unaware of their surroundings that they do not respond when friends speak to them, and they do not realize they have a problem.
Laboratory studies have shown that animals exhibit symptoms of drug withdrawal after cessation of prolonged marijuana administration. Some human studies have also demonstrated withdrawal symptoms such as irritability, stomach pain, aggression, and anxiety after cessation of oral administration of tetrahydrocannabinol (THC), marijuana's principal psychoactive component. Now, NIDA-supported researchers at McLean Hospital in Belmont, Massachusetts, and Columbia University in New York City have shown that individuals who regularly smoke marijuana experience withdrawal symptoms after they stop smoking the drug.
Studies at Columbia University in New York City have demonstrated that, in addition to aggression, marijuana smokers experience other withdrawal symptoms such as anxiety, stomach pain, and increased irritability during abstinence from the drug. "These results suggest that dependence may be an important consequence of repeated daily exposure to marijuana," says NIDA.
Early Marijuana:
Marijuana has been used as an agent for achieving euphoria since ancient times; it was described in a Chinese medical compendium traditionally considered to date from 2737 B.C. Its use spread from China to India and then to North Africa and reached Europe at least as early as A.D. 500. The first direct reference to a cannabis product as a psychoactive agent dates from 2737 BC, in the writings of the Chinese emperor Shen Nung.
The focus was on its powers as a medication for rheumatism, gout, malaria, and oddly enough, absent-mindedness. Mention was made of the intoxicating properties, but the medicinal value was considered more important. In India though, it was clearly used recreationally. The Muslims too used it recreationally for alcohol consumption was banned by the Koran. It was the Muslims who introduced hashish, whose popularity spread quickly throughout 12th century Persia (Iran) and North Africa.
Marijuana in America:
In 1545 the Spanish brought marijuana to the New World. The English introduced it in Jamestown in 1611 where it became a major commercial crop alongside tobacco and was grown as a source of fibre.
By 1890, hemp had been replaced by cotton as a major cash crop in southern states. Some patent medicines during this era contained marijuana, but it was a small percentage compared to the number containing opium or cocaine. It was in the 1920's that marijuana began to catch on. Some historians say its emergence was brought about by Prohibition. Its recreational use was restricted to jazz musicians and people in show business. "Reefer songs" became the rage of the jazz world. Marijuana clubs, called tea pads, sprang up in every major city.
These marijuana establishments were tolerated by the authorities because marijuana was not illegal and patrons showed no evidence of making a nuisance of themselves or disturbing the community. Marijuana was not considered a social threat.
Marijuana was listed in the United States Pharmacopeia from 1850 until 1942 and was prescribed for various conditions including labour pains, nausea, and rheumatism. Its use as an intoxicant was also commonplace from the 1850s to the 1930s. A campaign conducted in the 1930s by the U.S. Federal Bureau of Narcotics (now the Bureau of Narcotics and Dangerous Drugs) sought to portray marijuana as a powerful, addicting substance that would lead users into narcotics addiction.
It is still considered a "gateway" drug by some authorities. In the 1950s it was an accessory of the beat generation; in the 1960s it was used by college students and "hippies" and became a symbol of rebellion against authority.
The Controlled Substances Act of 1970 classified marijuana along with heroin and LSD as a Schedule I drug, i.e., having the relatively highest abuse potential and no accepted medical use. Most marijuana at that time came from Mexico, but in 1975 the Mexican government agreed to eradicate the crop by spraying it with the herbicide paraquat, raising fears of toxic side effects. Colombia then became the main supplier.
The "zero tolerance" climate of the Reagan and Bush administrations resulted in passage of strict laws and mandatory sentences for possession of marijuana and in heightened vigilance against smuggling at the southern borders.
The "war on drugs" thus brought with it a shift from reliance on imported supplies to domestic cultivation (particularly in Hawaii and California). Beginning in 1982 the Drug Enforcement Administration turned increased attention to marijuana farms in the United States, and there was a shift to the indoor growing of plants specially developed for small size and high yield. After over a decade of decreasing use, marijuana smoking began an upward trend once more in the early 1990s, especially among teenagers.
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This process will yield limited success when approached outside of a residential treatment facility particularly when detoxification is required. It is imperative that individuals entering treatment are given as much training and education as possible.
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